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  • BTK抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16347
    • 應(yīng)用 : 僅限于科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱: BTK抗原(重組蛋白)

英文名稱: BTK Antigen (Recombinant Protein)

別       名: Bruton tyrosine kinase; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1

相關(guān)類別: 抗原

儲       存: 冷凍(-20℃)

概述

Fusion protein corresponding to a region derived from 460-659 amino acids of human BTK

技術(shù)規(guī)格

Full name:

Bruton tyrosine kinase

Synonyms:

AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1

Swissprot:

Q06187

Gene Accession:

BC109079

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.