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  • PDGFRB抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17027
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱: PDGFRB抗原(重組蛋白)

英文名稱: PDGFRB Antigen (Recombinant Protein)

名: IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述


Fusion protein corresponding to C terminal 212 amino acids of human PDGFRB

技術(shù)規(guī)格

Full name:

Platelet-derived growth factor receptor, beta polypeptide

Synonyms:

IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1

Swissprot:

P09619

Gene Accession:

BC032224

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.