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    • PRMT7抗原（重組蛋白）

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      價(jià)格：￥
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW17091
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 ：1mg/100ug
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    中文名稱(chēng)： PRMT7抗原（重組蛋白）

    英文名稱(chēng)： PRMT7 Antigen (Recombinant Protein)

    儲(chǔ)       存： 冷凍（-20℃）

    相關(guān)類(lèi)別： 抗原

    概述

    Fusion protein corresponding to a region derived from 526-692 amino acids of human PRMT7

    技術(shù)規(guī)格

    Full name:

    Protein arginine methyltransferase 7

    Swissprot:

    Q9NVM4

    Gene Accession:

    BC000146

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).