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中文名稱： DNM1L抗原（重組蛋白）

英文名稱： DNM1L Antigen (Recombinant Protein)

別名： DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 461-710 amino acids of human DNM1L

技術規(guī)格：

Full name:	dynamin 1 like
Synonyms:	DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV
Swissprot:	O00429
Gene Accession:	BC024590
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

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