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中文名稱： SOCS2抗原（重組蛋白）

英文名稱： SOCS2 Antigen (Recombinant Protein)

別名： CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 31-198 amino acids of human SOCS2

技術(shù)規(guī)格

Full name:	suppressor of cytokine signaling 2
Synonyms:	CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
Swissprot:	O14508
Gene Accession:	BC010399
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

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