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  • IL1R2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17910
    • 應用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱:IL1R2抗原(重組蛋白)

英文名稱: IL1R2 Antigen (Recombinant Protein)

儲      存: 冷凍(-20℃)

相關類別: 抗原

概述

Fusion protein corresponding to a region derived from 25-239 amino acids of human IL1R2


技術規(guī)格

Full name:

Interleukin-1 receptor type 2

Synonyms:

IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2

Swissprot:

P27930

Gene Accession:

BC039031

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.