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中文名稱：IVD 抗原（重組蛋白）

英文名稱： IVD Antigen (Recombinant Protein)

別名： isovaleryl-CoA dehydrogenase; ACAD2

儲存： 冷凍（-20℃）

相關類別： 抗原

概述

Fusion protein corresponding to a region derived from 224-423 amino acids of human IVD

技術規(guī)格

Full name:	isovaleryl-CoA dehydrogenase
Synonyms:	ACAD2
Swissprot:	P26440
Gene Accession:	BC017202
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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