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    • VPREB3 抗原（重組蛋白）

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      價格：￥
      • 品牌 : 通蔚生物
      • 目錄號 : TW6413
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 ：1mg/100ug
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    中文名稱： VPREB3 抗原（重組蛋白）

    英文名稱： VPREB3 Antigen (Recombinant Protein)

    別     名： pre-B lymphocyte 3; 8HS20; N27C7-2

    相關(guān)類別    ：抗原

    儲     存： 冷凍（-20℃）

    概     述

    Fusion protein corresponding to a region derived from 21-123 amino acids of human VPREB3

    技術(shù)規(guī)格

    Full name:

    pre-B lymphocyte 3

    Synonyms:

    8HS20; N27C7-2

    Swissprot:

    Q9UKI3

    Gene Accession:

    BC020666

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.