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    • 小鼠抗CDC42單克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW6611
      • 應用 : 僅限于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 ：100ul
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    中文名稱：小鼠抗CDC42單克隆抗體

    英文名稱： Anti-CDC42 mouse monoclonal antibody
    相關類別： 一抗

    儲       存： 冷凍（-20℃）
    宿      主： Mouse

    抗      原： CDC42
    反應種屬： Human
    標 記 物： Unconjugate

    克隆類型： mouse monoclonal
    技術規(guī)格

    Background:

    The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.

    Applications:

    ELISA, WB

    Name of antibody:

    CDC42

    Immunogen:

    Fusion protein of human CDC42

    Full name:

    cell division cycle 42

    Synonyms:

    TKS; G25K; CDC42Hs

    SwissProt:

    P60953

    WB Predicted band size:

    21 kDa

    WB Positive control:

    SW480 whole cell lysate

    WB Recommended dilution:

    1000-5000