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  • RHOH抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4562
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ug
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中文名稱: RHOH抗原(重組蛋白)

英文名稱: RHOH Antigen (Recombinant Protein)

別     名: TTF; ARHH

儲(chǔ)     存: 冷凍(-20℃)

相關(guān)類別:抗原

概     述

Fusion protein corresponding to a region derived from 1-191 amino acids of human RHOH

技術(shù)規(guī)格

Full name:

ras homolog family member H

Synonyms:

TTF; ARHH

Swissprot:

Q15669

Gene Accession:

BC014261

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.